- FeCl3 catalyzed Prins-type cyclization for the synthesis of highly substituted indenes: application to the total synthesis of (±)-jungianol and epi-jungianol.
FeCl3 catalyzed Prins-type cyclization for the synthesis of highly substituted indenes: application to the total synthesis of (±)-jungianol and epi-jungianol.
Organic letters (2013-01-16)
Dattatraya H Dethe, Ganesh Murhade
PMID23317410
RESUMO
A novel approach was developed for the synthesis of highly substituted indene derivatives, using an FeCl(3) catalyzed Prins-type cyclization reaction which was further applied in the total synthesis of jungianol and epi-jungianol.
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