- Highly enantioselective Friedel-Crafts alkylation reaction catalyzed by rosin-derived tertiary amine-thiourea: synthesis of modified chromanes with anticancer potency.
Highly enantioselective Friedel-Crafts alkylation reaction catalyzed by rosin-derived tertiary amine-thiourea: synthesis of modified chromanes with anticancer potency.
Chemical communications (Cambridge, England) (2011-11-15)
Xianxing Jiang, Lipeng Wu, Yanhong Xing, Long Wang, Shoulei Wang, Zongyao Chen, Rui Wang
PMID22080190
RESUMO
We present herein for the first time the synthesis and preliminary biological evaluation of various modified chromanes via a rosin-derived tertiary amine-thiourea-catalyzed highly enantioselective Friedel-Crafts alkylation reaction.
MATERIAIS