Pular para o conteúdo
Merck

[Reaction of pyridinium salts with active methylene compounds].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan (2006-02-08)
Reiko Fujita, Masato Hoshino, Yasuhiro Nishiuchi, Hiroshi Tomisawa
RESUMO

The carbon-carbon bond-forming reactions of 1-methyl-2-methylthiophenylpyridinium iodides with active methylene compounds (such as dimethyl malonate, malononitrile) using NaH as a base gave the 2-substituted methylene-1,2-dihydropyridine derivatives.

MATERIAIS
Número do produto
Marca
Descrição do produto

Sigma-Aldrich
Dimethyl malonate, 98%
Sigma-Aldrich
Dimethyl malonate, purum, ≥96.0% (GC)