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Merck

PhenoFluor: Practical Synthesis, New Formulation, and Deoxyfluorination of Heteroaromatics.

Organic process research & development (2014-09-02)
Teppei Fujimoto, Fabian Becker, Tobias Ritter
RESUMO

We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluorination with PhenoFluor to heteroaromatics.

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Sigma-Aldrich
2-Chloro-1,3-bis(2,6-diisopropylphenyl)imidazolium chloride, ≥95%