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D6571

3′,4′-Dimethoxyflavone

Sinônimo(s):

2-(3,4-Dimethoxyphenyl)chromen-4-one, 3′,4′-DMF

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Para você/SKUDisponibilidadePreço
5 mg
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R$ 728,00
R$ 618,80
25 mg
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R$ 2.904,00

Sobre este item

Fórmula empírica (Notação de Hill):
C17H14O4
Número CAS:
4143-62-8
Peso molecular:
282.29
NACRES:
NA.77
PubChem Substance ID:
329798831
UNSPSC Code:
12352200
MDL number:
MFCD00143009
Assay:
≥98% (HPLC)
Form:
powder

R$ 618,80

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assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: ≥20 mg/mL

storage temp.

room temp

SMILES string

COc1ccc(cc1OC)C2=CC(=O)c3ccccc3O2

InChI

1S/C17H14O4/c1-19-15-8-7-11(9-17(15)20-2)16-10-13(18)12-5-3-4-6-14(12)21-16/h3-10H,1-2H3

InChI key

ZGHORMOOTZTQFL-UHFFFAOYSA-N

Application

3′,4′-Dimethoxyflavone has been used in urease inhibition assay.

Biochem/physiol Actions

3′,4′-dimethoxyflavone is a competitive antagonist of the AhR that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines. The compound blocks transformation of the cytosolic AhR complex, and formation of nuclear AhR complexes.
3′,4′-dimethoxyflavone is a competitive antagonist of the aryl hydrocarbon receptor (AhR) that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines.
3′,4′-Dimethoxyflavone is a flavone compound, which has the ability to prevent the production and accumulation of poly (ADP-ribose) (PAR) polymer. It guards against N-methyl-D-aspartate (NMDA) toxicity in cortical neurons. 3′,4′-Dimethoxyflavone is a member of the class of plant-derived polyphenolic flavonoids. It is known to have antioxidant, anti-cancer, anti-inflammatory, anti-atherogenic, hypolipidemic and neuroprotective or neurotrophic effects.

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Este Item
SML0699T4080SML1052
3′,4′-Dimethoxyflavone

Sigma-Aldrich

D6571

3′,4′-Dimethoxyflavone

4′-Methoxyflavone ≥97% (HPLC)

Sigma-Aldrich

SML0699

4′-Methoxyflavone

6, 2′, 4′-trimethoxyflavone ≥98% (HPLC)

Sigma-Aldrich

T4080

6, 2′, 4′-trimethoxyflavone

2-D08 ≥98% (HPLC)

Sigma-Aldrich

SML1052

2-D08

form

powder

form

lyophilized powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥97% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: >5 mg/mL

solubility

DMSO: 20 mg/mL, clear

color

white to off-white

color

white

color

yellow

color

white to beige

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Lot/Batch Number

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