The stability of this product in solution has not been determined. Various sources suggest that stock solutions may be stored in aliquots at ?20°C for 1 month and at ?80°C for 6 months. This information has not been validated.
A265
ARL 67156 trisodium salt hydrate
≥98% (HPLC), solid, ecto-ATPase inhibitor
Sinônimo(s):
6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5′-triphosphate trisodium salt hydrate, FPL 67156
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| Para você/SKU | Disponibilidade | Preço |
|---|---|---|
5 mg | Previsão de entrega em01 de junho de 2026deCajamar | R$ 2.753,00 |
25 mg | Verificar disponibilidade no carrinho | R$ 9.592,00 |
Sobre este item
Fórmula empírica (Notação de Hill):
C15H21Br2N5Na3O12P3 · xH2O
Número CAS:
Peso molecular:
785.05 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Assistência Técnica
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Estamos aqui para ajudarNome do produto
ARL 67156 trisodium salt hydrate, ≥98% (HPLC), solid
Quality Segment
assay
≥98% (HPLC)
form
solid
color
white to off-white
solubility
H2O: >20 mg/mL, DMSO: insoluble
storage temp.
−20°C
SMILES string
O.[Na+].[Na+].[Na+].CCN(CC)c1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)C(Br)(Br)P([O-])([O-])=O)[C@@H](O)[C@H]3O
InChI
1S/C15H24Br2N5O12P3.3Na.H2O/c1-3-21(4-2)12-9-13(19-6-18-12)22(7-20-9)14-11(24)10(23)8(33-14)5-32-37(30,31)34-36(28,29)15(16,17)35(25,26)27;;;;/h6-8,10-11,14,23-24H,3-5H2,1-2H3,(H,28,29)(H,30,31)(H2,25,26,27);;;;1H2/q;3*+1;/p-3/t8-,10-,11-,14-;;;;/m1..../s1
InChI key
UWMONIJVKGTUGE-OPKBHZIBSA-K
Gene Information
human ... ENTPD2(954)
General description
ARL 67156, a nucleotide/ATP analog is a competitive inhibitor of CD39.[1] This ecto-ATPase inhibitor[2] is presumed to be metabolically stable in biological studies due to its β, γ-dibromomethylene bridge.[1]
ARL-67156 preferentially inhibits the degradation of ADP compared to the degradation of ATP in the murine colon. It is commonly employed to inhibit ATP hydrolysis in tissue preparations.
Application
ARL 67156 trisodium salt hydrate has been used:
- to prevent ATP degradation during cerebrospinal fluid extraction[3]
- as an ATPase inhibitor in ATP quantification assay for preventing ATP degradation in cytoplasm and mitochondrion[4]
- as an ecto-ATPase inhibitor to treat cancer cells for ATP release assay[5]
Biochem/physiol Actions
ecto-ATPase inhibitor; prevents metabolism of P2 purinoceptor agonists.
1 of 1
Este Item | |||
|---|---|---|---|
| form solid | form solid | form solid | form - |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. - | storage temp. −20°C |
| solubility H2O: >20 mg/mL, DMSO: insoluble | solubility H2O: soluble | solubility H2O: soluble | solubility DMSO: 1.1 mg/mL, H2O: >10 mg/mL |
| color white to off-white | color white | color off-white to light tan | color - |
Classe de armazenamento
11 - Combustible Solids
wgk
WGK 3
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What is the stability of Product A265, ARL 67156 trisodium salt hydrate, in solution (water)?
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