C-terminal 6His-tagged, recombinant, human full length, PAK3.
mitosis
Product Source: PAK3 expressed by baculovirus in Sf21 cells.
Aplicação
Research Category Inflammation & Immunology
Ações bioquímicas/fisiológicas
Protein Target: PAK3
Target Sub-Family: STE
Qualidade
routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).
forma física
Ni2+/NTA-agarose
Armazenamento e estabilidade
6 months at -70°C from date of shipment
Outras notas
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Informações legais
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Trends in neurosciences, 25(4), 191-199 (2002-05-10)
For several decades, it has been known that mental retardation (MR) is associated with abnormalities in dendrites and dendritic spines. The recent cloning of seven genes that cause nonspecific MR when mutated provides important insights in the cellular mechanisms that
The p21-activated protein kinase gamma-PAK, also known as PAK2, has very different properties from the other two highly conserved isoforms of the PAK family, alpha-PAK (PAK1) and beta-PAK (PAK3). gamma-PAK has cytostatic activity, as shown by inhibition of cleavage of
The international journal of biochemistry & cell biology, 34(7), 713-717 (2002-04-16)
The p21-activated kinases (Paks) are serine/threonine protein kinases that bind to and, in some cases, are stimulated by activated forms of the small GTPases, Cdc42 and Rac. With the recent discovery of several novel isoforms, Paks are now categorized into
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