Pular para o conteúdo
Merck

TNFRSF11B

tumor necrosis factor receptor superfamily, member 11b

Sinônimos:
OCIF, OPG, TR1
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4982) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(18383) tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
  • Rat(25341) tumor necrosis factor receptor superfamily, member 11b
  • cow(523822) tumor necrosis factor receptor superfamily, member 11b
  • chicken(378803) tumor necrosis factor receptor superfamily, member 11b
  • Zebrafish(407674) tumor necrosis factor receptor superfamily, member 11b
  • dog(482025) tumor necrosis factor receptor superfamily, member 11b
  • Goat(100860896) tumor necrosis factor receptor superfamily, member 11b
  • Domestic Rabbit(100348133) tumor necrosis factor receptor superfamily, member 11b
  • domestic guinea pig(100715850) tumor necrosis factor receptor superfamily, member 11b
  • naked mole-rat(101709512) tumor necrosis factor receptor superfamily, member 11b
  • Horse(100065885) tumor necrosis factor receptor superfamily, member 11b
  • domestic cat(101096878) tumor necrosis factor receptor superfamily, member 11b

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Número do produto
Descrição
Espécies
Human Osteoprotegerin / TNFRSF11b ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espécies
human
Mouse Osteoprotegerin ELISA Kit, for serum, plasma, cell culture supernatant,
Espécies
mouse
Porcine OPG ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espécies

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Tnfrsf11B Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-Osteoprotegerin antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reatividade de espécies
mouse
Aplicação
immunohistochemistry
neutralization

western blot
Anti-Osteoprotegerin/TNFRSF11B Antibody, from rabbit, purified by affinity chromatography,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-TNFRSF11B antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-TR11B antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse
Aplicação
ELISA
western blot

Proteins

Número do produto
Descrição
Espécies
Osteoprotegerin/Fc Chimera from mouse, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Espécies
mouse
Osteoprotegerin (OPG) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human TNFRSF11B,
Espécies
human