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Merck

SORT1

sortilin 1

Sinônimos:
Gp95, LDLCQ6, NT3
Espécies:
ID UniProtKB:
ID do gene:
  • Human(6272) Summary: This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq, Jul 2008]
  • Mouse(20661) sortilin 1
  • Rat(83576) sortilin 1
  • cow(511591) sortilin 1
  • sheep(101104538) sortilin 1
  • domestic guinea pig(100718269) sortilin 1
  • dog(479915) sortilin 1
  • domestic cat(101090199) sortilin 1
  • Horse(100061385) sortilin 1
  • chicken(100858592) sortilin 1
  • naked mole-rat(101698000) sortilin 1

Custom & Knockdown Gene Products

ELISA

Número do produto
Descrição
Espécies
Human Sortilin ELISA, for serum, plasma and cell culture supernatants,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Sortilin Antibody, clone 2F18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
chimpanzee, mouse, rat
Aplicação
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Sortilin Antibody, clone F11, clone F11, from mouse,
Reatividade de espécies
human, mouse
Aplicação
ELISA
immunocytochemistry

immunohistochemistry

western blot
Anti-SORT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-Sortilin Antibody, serum, Chemicon®,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Monoclonal Anti-SORT1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL6528, purified immunoglobulin, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse
Aplicação
immunohistochemistry
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human SORT1,
Espécies
human
MISSION® esiRNA, targeting mouse Sort1,
Espécies
mouse