RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
Sinônimos:
AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Espécies:
Human RUNX1T1 (862), Mouse Runx1t1 (12395), Rat Runx1t1 (362489), domestic guinea pig Runx1t1 (100724443), naked mole-rat Runx1t1 (101707177), cow RUNX1T1 (538628), sheep RUNX1T1 (101113340), dog RUNX1T1 (487044), domestic cat RUNX1T1 (101080942), Horse RUNX1T1 (100050630) ...Mais
ID UniProtKB:
ID do gene:
- Human(862) Summary: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
- Mouse(12395) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- Rat(362489) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- domestic guinea pig(100724443) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- naked mole-rat(101707177) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- cow(538628) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- sheep(101113340) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- dog(487044) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- domestic cat(101080942) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- Horse(100050630) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- Zebrafish(767809) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
- chicken(395503) runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-RUNX1T1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-RUNX1T1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
proximity ligation assay
western blot
western blot
Anti-RUNX1T1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-RUNX1T1 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, human, pig, rabbit
Aplicação
immunohistochemistry
western blot
western blot
esiRNA
Número do produto
Descrição
Espécies