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Merck

PTGIS

prostaglandin I2 (prostacyclin) synthase

Sinônimos:
CYP8, CYP8A1, PGIS, PTGI
Espécies:
ID UniProtKB:
ID do gene:
  • Human(5740) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
  • Mouse(19223) prostaglandin I2 (prostacyclin) synthase
  • Rat(25527) prostaglandin I2 (prostacyclin) synthase
  • dog(485919) prostaglandin I2 (prostacyclin) synthase
  • Goat(100860894) prostaglandin I2 (prostacyclin) synthase
  • cow(282021) prostaglandin I2 (prostacyclin) synthase
  • domestic guinea pig(100734621) prostaglandin I2 (prostacyclin) synthase
  • Zebrafish(559148) prostaglandin I2 (prostacyclin) synthase
  • sheep(101116418) prostaglandin I2 (prostacyclin) synthase
  • Horse(100071412) prostaglandin I2 (prostacyclin) synthase
  • naked mole-rat(101700601) prostaglandin I2 (prostacyclin) synthase
  • domestic cat(101082050) prostaglandin I2 (prostacyclin) synthase

Custom & Knockdown Gene Products

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PTGIS antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, human, mouse, rat
Aplicação
western blot
Anti-PTGIS antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
Anti-PTGIS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-PTGIS antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Monoclonal Anti-PTGIS, (C-terminal) antibody produced in mouse, clone 3B11, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human PTGIS,
Espécies
human
MISSION® esiRNA, targeting mouse Ptgis,
Espécies
mouse