PSMC5
proteasome (prosome, macropain) 26S subunit, ATPase, 5
Sinônimos:
S8, SUG-1, SUG1, TBP10, TRIP1, p45, p45/SUG
Espécies:
Human PSMC5 (5705), Mouse Psmc5 (19184), Rat Psmc5 (81827), Zebrafish psmc5 (445285), chicken PSMC5 (428274), domestic guinea pig Psmc5 (100717173), naked mole-rat Psmc5 (101710432), sheep PSMC5 (101104076), cow PSMC5 (282015), Horse PSMC5 (100053987) ...Mais
ID UniProtKB:
ID do gene:
- Human(5705) Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
- Mouse(19184) protease (prosome, macropain) 26S subunit, ATPase 5
- Rat(81827) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- Zebrafish(445285) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- chicken(428274) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- domestic guinea pig(100717173) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- naked mole-rat(101710432) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- sheep(101104076) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- cow(282015) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- Horse(100053987) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- domestic cat(101097360) proteasome (prosome, macropain) 26S subunit, ATPase, 5
- dog(480478) proteasome (prosome, macropain) 26S subunit, ATPase, 5
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti PSMC5 Antibody, clone 24GB1500, Rabbit Monoclonal, clone 24GB1500, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reatividade de espécies
human, rat
Aplicação
flow cytometry
western blot
western blot
Anti-PSMC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-PSMC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot