PCSK1
proprotein convertase subtilisin/kexin type 1
Sinônimos:
BMIQ12, NEC1, PC1, PC3, SPC3
Espécies:
Human PCSK1 (5122), Mouse Pcsk1 (18548), Rat Pcsk1 (25204), domestic guinea pig Pcsk1 (100732445), naked mole-rat Pcsk1 (101704290), cow PCSK1 (281967), domestic cat PCSK1 (101082627), Zebrafish pcsk1 (100005716), chicken PCSK1 (769230), Horse PCSK1 (100064886)
ID UniProtKB:
ID do gene:
- Human(5122) Summary: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]
- Mouse(18548) proprotein convertase subtilisin/kexin type 1
- Rat(25204) proprotein convertase subtilisin/kexin type 1
- domestic guinea pig(100732445) proprotein convertase subtilisin/kexin type 1
- naked mole-rat(101704290) proprotein convertase subtilisin/kexin type 1
- cow(281967) proprotein convertase subtilisin/kexin type 1
- domestic cat(101082627) proprotein convertase subtilisin/kexin type 1
- Zebrafish(100005716) proprotein convertase subtilisin/kexin type 1
- chicken(769230) proprotein convertase subtilisin/kexin type 1
- Horse(100064886) proprotein convertase subtilisin/kexin type 1
- dog(479149) proprotein convertase subtilisin/kexin type 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PCSK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Monoclonal Anti-PCSK1, (C-terminal) antibody produced in mouse, clone 2G12, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
western blot
Monoclonal Anti-PCSK1 antibody produced in mouse, clone 3D2, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-PCSK1 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human
Aplicação
immunohistochemistry
western blot
western blot
Anti-PCSK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
immunohistochemistry