PARN
poly(A)-specific ribonuclease
Sinônimos:
DAN
Espécies:
Human PARN (5073), Mouse Parn (74108), Rat Parn (360464), domestic guinea pig Parn (100732149), naked mole-rat Parn (101715275), cow PARN (524155), Zebrafish parn (791461), Domestic Rabbit PARN (100351489), domestic cat PARN (101100021), dog PARN (479839) ...Mais
ID UniProtKB:
ID do gene:
- Human(5073) Summary: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(74108) poly(A)-specific ribonuclease (deadenylation nuclease)
- Rat(360464) poly(A)-specific ribonuclease
- domestic guinea pig(100732149) poly(A)-specific ribonuclease
- naked mole-rat(101715275) poly(A)-specific ribonuclease
- cow(524155) poly(A)-specific ribonuclease
- Zebrafish(791461) poly(A)-specific ribonuclease (deadenylation nuclease)
- Domestic Rabbit(100351489) poly(A)-specific ribonuclease
- domestic cat(101100021) poly(A)-specific ribonuclease
- dog(479839) poly(A)-specific ribonuclease
- chicken(416423) poly(A)-specific ribonuclease
- sheep(101112185) poly(A)-specific ribonuclease
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Número do produto
Descrição
Espécies
Mouse Parn / Poly(A)-specific Ribonuclease PARN ELISA Kit, for serum, plasma and cell culture supernatants,
Espécies
mouse
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-PARN antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunofluorescence
western blot
western blot
Anti-PARN antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Anti-PARN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
western blot
Anti-PARN antibody produced in rabbit, IgG fraction of antiserum,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
western blot