PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
Sinônimos:
AR-JP, LPRS2, PDJ, PRKN
Espécies:
Human PARK2 (5071), Mouse Park2 (50873), Rat Park2 (56816), cow PARK2 (530858), naked mole-rat Park2 (101700770), domestic guinea pig Park2 (100724550), Horse PARK2 (100057832), Zebrafish park2 (550328), chicken PARK2 (421577), dog PARK2 (612316) ...Mais
ID UniProtKB:
ID do gene:
- Human(5071) Summary: The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
- Mouse(50873) Parkinson disease (autosomal recessive, juvenile) 2, parkin
- Rat(56816) parkinson protein 2, E3 ubiquitin protein ligase
- cow(530858) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- naked mole-rat(101700770) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- domestic guinea pig(100724550) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- Horse(100057832) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- Zebrafish(550328) Parkinson disease (autosomal recessive, juvenile) 2, parkin
- chicken(421577) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- dog(612316) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- domestic cat(101098228) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- sheep(101113503) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Parkin antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Parkin Antibody, a.a. 305-323, serum, Chemicon®,
Reatividade de espécies
human, rat
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Parkin Antibody, clone PRK8, ascites fluid, clone PRK8, Upstate®,
Reatividade de espécies
human, mouse
Aplicação
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-PARK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
immunohistochemistry
ANTI-PARKIN(C-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human, mouse
Aplicação
flow cytometry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
esiRNA
Número do produto
Descrição
Espécies