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Merck

NDUFS1

NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

Sinônimos:
CI-75Kd, CI-75k, PRO1304
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4719) Summary: The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(227197) NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • Rat(301458) NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • Zebrafish(493605) NADH dehydrogenase (ubiquinone) Fe-S protein 1
  • chicken(424102) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • domestic guinea pig(100726311) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • naked mole-rat(101698993) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • cow(288380) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • sheep(101115434) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • Goat(100861376) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • domestic cat(101100747) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • dog(478880) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
  • Horse(100066330) NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Complex I-75kD Antibody, from rabbit, purified by affinity chromatography,
Reatividade de espécies
bovine, chimpanzee, human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-NDUFS1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-NDUFS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
Anti-NDUFS1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-NDUFS1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
bovine, canine, human, mouse, rat
Aplicação
ELISA
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
1,1-Dimethylbiguanide hydrochloride, 97%,
Espécies
human
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
Metformin hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Ndufs1,
Espécies
mouse
MISSION® esiRNA, targeting human NDUFS1,
Espécies
human