Pular para o conteúdo
Merck

MMP8

matrix metallopeptidase 8 (neutrophil collagenase)

Sinônimos:
CLG1, HNC, MMP-8, PMNL-CL
Espécies:
ID UniProtKB:
ID do gene:
  • Human(4317) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Mouse(17394) matrix metallopeptidase 8
  • Rat(63849) matrix metallopeptidase 8
  • domestic guinea pig(100724670) matrix metallopeptidase 8 (neutrophil collagenase)
  • naked mole-rat(101716969) matrix metallopeptidase 8 (neutrophil collagenase)
  • sheep(101120601) matrix metallopeptidase 8 (neutrophil collagenase)
  • domestic cat(101080995) matrix metallopeptidase 8 (neutrophil collagenase)
  • Horse(100069005) matrix metallopeptidase 8 (neutrophil collagenase)
  • cow(100336575) matrix metallopeptidase 8 (neutrophil collagenase)
  • dog(489429) matrix metallopeptidase 8 (neutrophil collagenase)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Número do produto
Descrição
Espécies
Human MMP-8 ELISA Kit, for serum, plasma, conditioned medium, urine,
Espécies
human
Rat MMP-8 ELISA Kit, for serum, plasma, cell culture supernatant,
Espécies
mouse

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-MMP8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-Mmp8 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Doxycycline monohydrate, ,
Espécies
human
α-Sexithiophene, ,
Espécies
human, rat
Marimastat, ≥98% (HPLC),
Espécies
human, rat, mouse
CP-101537, ≥98% (HPLC),
Espécies
human, rat, mouse
CP-471474, ≥98% (HPLC),
Espécies
human, rat, mouse

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human MMP8,
Espécies
human