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Merck

IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

Sinônimos:
IMPD, IMPD1, LCA11, RP10, sWSS2608
Espécies:
ID UniProtKB:
ID do gene:
  • Human(3614) Summary: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
  • Mouse(23917) inosine 5'-phosphate dehydrogenase 1
  • Rat(362329) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Domestic Rabbit(100357217) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • dog(608783) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic guinea pig(100717020) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • naked mole-rat(101720344) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic cat(101084274) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Horse(100071737) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • sheep(101104144) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • cow(504305) IMP (inosine 5'-monophosphate) dehydrogenase 1

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Monoclonal Anti-IMPDH1 antibody produced in mouse, clone 3G6, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-IMPDH1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-IMPDH1 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
immunohistochemistry
western blot
Anti-IMPDH1 Antibody, clone 4F9.1, clone 4F9.1, from mouse,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
6-Thioguanine, ≥98%,
Espécies
human
Mycophenolic acid, ≥98%,
Espécies
human
Mycophenolic acid, powder, BioReagent, suitable for cell culture,
Espécies
human
6-Thioguanine, Hybri-Max, 50 ×, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Espécies
human
Mycophenolate mofetil, ≥98% (HPLC),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human IMPDH1,
Espécies
human
MISSION® esiRNA, targeting mouse Impdh1,
Espécies
mouse