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Merck

IDH2

isocitrate dehydrogenase 2 (NADP+), mitochondrial

Sinônimos:
D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
Espécies:
ID UniProtKB:
ID do gene:
  • Human(3418) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq, Jul 2008]
  • Mouse(269951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Rat(361596) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Thale Cress(816218) Isocitrate dehydrogenase [NAD] regulatory subunit 2
  • Zebrafish(386951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • dog(479043) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • chicken(431056) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • Domestic Rabbit(100340796) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • sheep(101102843) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • cow(327669) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • domestic cat(101082315) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • naked mole-rat(101708667) isocitrate dehydrogenase 2 (NADP+), mitochondrial
  • domestic guinea pig(100726681) isocitrate dehydrogenase 2 (NADP+), mitochondrial

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-IDH2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
bovine, canine, human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot
Monoclonal Anti-IDH2 antibody produced in mouse, clone 5F11, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
immunohistochemistry

western blot
Anti-IDH2 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
western blot
Anti-IDH2 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot
Anti-IDH2 antibody produced in rabbit, ,
Reatividade de espécies
human, mouse, rat
Aplicação
immunohistochemistry
western blot

Kits

Número do produto
Descrição
Espécies
IDH Activity Assay Kit, sufficient for 100 colorimetric tests,
Espécies
mouse, rat, human

Proteins

Número do produto
Descrição
Espécies
IDH2, FLAG® -Tag, recombinant, expressed in baculovirus infected Sf9 cells,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human IDH2,
Espécies
human
MISSION® esiRNA, targeting mouse Idh2,
Espécies
mouse