Pular para o conteúdo
Merck

GUCA2B

guanylate cyclase activator 2B (uroguanylin)

Sinônimos:
GCAP-II, UGN
Espécies:
ID UniProtKB:
ID do gene:
  • Human(2981) Summary: This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. [provided by RefSeq, Oct 2011]
  • Mouse(14916) guanylate cyclase activator 2b (retina)
  • Rat(64055) guanylate cyclase activator 2B
  • dog(100684829) guanylate cyclase activator 2B (uroguanylin)
  • naked mole-rat(101720311) guanylate cyclase activator 2B (uroguanylin)
  • domestic guinea pig(100135535) guanylate cyclase activator 2b (retina)
  • domestic cat(101092381) guanylate cyclase activator 2B (uroguanylin)
  • Zebrafish(325935) guanylate cyclase activator 2B (uroguanylin)
  • cow(515664) guanylate cyclase activator 2B (uroguanylin)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Kynurenic acid, ≥98%,
Espécies
rat, human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
ANTI-GUCA2B (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

Proteins

Número do produto
Descrição
Espécies
Uroguanylin, ≥90% (HPLC),
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human GUCA2B,
Espécies
human