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Merck

GP1BA

glycoprotein Ib (platelet), alpha polypeptide

Sinônimos:
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
Espécies:
ID UniProtKB:
ID do gene:
  • Human(2811) Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]
  • Mouse(14723) glycoprotein 1b, alpha polypeptide
  • Rat(691992) glycoprotein Ib (platelet), alpha polypeptide
  • chicken(420059) glycoprotein Ib (platelet), alpha polypeptide
  • naked mole-rat(101717127) glycoprotein Ib (platelet), alpha polypeptide
  • domestic guinea pig(100717535) glycoprotein Ib (platelet), alpha polypeptide
  • sheep(101109891) glycoprotein Ib (platelet), alpha polypeptide
  • cow(504977) glycoprotein Ib (platelet), alpha polypeptide
  • domestic cat(101092307) glycoprotein Ib (platelet), alpha polypeptide
  • dog(403638) glycoprotein Ib (platelet), alpha polypeptide

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ELISA

Número do produto
Descrição
Espécies
Human CD42b ELISA, for serum, plasma and cell culture supernatants,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CD42B antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP219, affinity isolated antibody,
Reatividade de espécies
dog, human, mouse
Aplicação
flow cytometry
immunohistochemistry
Monoclonal Anti-CD42b antibody produced in mouse, clone HIP1, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human, nonhuman primates
Aplicação
flow cytometry
Anti-GP1BA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Monoclonal Anti-CD42b antibody produced in mouse, clone AK2,
Reatividade de espécies
human
Aplicação
flow cytometry
Anti-CD42b/GP1BA Antibody, clone 1C9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human
Aplicação
affinity binding assay
immunocytochemistry

western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Gp1ba,
Espécies
mouse
MISSION® esiRNA, targeting human GP1BA,
Espécies
human