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Merck

DUSP7

dual specificity phosphatase 7

Sinônimos:
MKPX, PYST2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1849) Summary: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]
  • Mouse(235584) dual specificity phosphatase 7
  • Rat(300980) dual specificity phosphatase 7
  • naked mole-rat(101699953) dual specificity phosphatase 7
  • domestic guinea pig(100723574) dual specificity phosphatase 7
  • cow(785016) dual specificity phosphatase 7
  • sheep(101112604) dual specificity phosphatase 7
  • Zebrafish(327246) dual specificity phosphatase 7
  • chicken(415891) dual specificity phosphatase 7
  • domestic cat(101101624) dual specificity phosphatase 7
  • dog(484742) dual specificity phosphatase 7

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-DUSP7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot
Anti-DUSP7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
Anti-DUSP7, (N-terminal) antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
western blot

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Dusp7,
Espécies
mouse
MISSION® esiRNA, targeting human DUSP7,
Espécies
human