CREBBP
CREB binding protein
Sinônimos:
CBP, KAT3A, RSTS
Espécies:
Human CREBBP (1387), Mouse Crebbp (12914), Rat Crebbp (54244), Zebrafish crebbp (100535787), Horse CREBBP (100069613), chicken CREBBP (416667), sheep CREBBP (101123600), domestic guinea pig Crebbp (100716770), naked mole-rat Crebbp (101714025), dog CREBBP (479866) ...Mais
ID UniProtKB:
ID do gene:
- Human(1387) Summary: This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
- Mouse(12914) CREB binding protein
- Rat(54244) CREB binding protein
- Zebrafish(100535787) CREB binding protein
- Horse(100069613) CREB binding protein
- chicken(416667) CREB binding protein
- sheep(101123600) CREB binding protein
- domestic guinea pig(100716770) CREB binding protein
- naked mole-rat(101714025) CREB binding protein
- dog(479866) CREB binding protein
- domestic cat(101094471) CREB binding protein
- cow(505453) CREB binding protein
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CBP antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-CREBBP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-CBP Antibody, clone 3N20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reatividade de espécies
human, rat
Aplicação
affinity binding assay
immunocytochemistry
immunohistochemistry
immunocytochemistry
immunohistochemistry
Anti-CREBBP antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicação
immunohistochemistry
western blot
western blot
Anti-CREB-BP antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse
Aplicação
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Proteins
Número do produto
Descrição
Espécies
CBP (1319-1710), GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human
KAT3A (518-1207), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espécies
human