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Merck

CDK8

cyclin-dependent kinase 8

Sinônimos:
K35
Espécies:
ID UniProtKB:
ID do gene:
  • Human(1024) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq, Jul 2008]
  • Mouse(264064) cyclin-dependent kinase 8
  • domestic guinea pig(100718250) cyclin-dependent kinase 8
  • naked mole-rat(101719987) cyclin-dependent kinase 8
  • sheep(101115551) cyclin-dependent kinase 8
  • Domestic Rabbit(100353845) cyclin-dependent kinase 8
  • domestic cat(101086278) cyclin-dependent kinase 8
  • Zebrafish(373868) cyclin-dependent kinase 8
  • cow(507149) cyclin-dependent kinase 8
  • dog(486035) cyclin-dependent kinase 8
  • chicken(428080) cyclin-dependent kinase 8
  • Horse(100050819) cyclin-dependent kinase 8
  • fruit fly(39157) Cyclin-dependent kinase 8

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Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CDK8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
western blot
ANTI-CDK8 antibody produced in mouse, clone 5H4, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
western blot
Anti-CDK8 Antibody, clone 7L5X2, Rabbit Monoclonal, ,
Reatividade de espécies
human, rat
Aplicação
western blot
Anti-CDK8 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse
Aplicação
ELISA
western blot
Anti-CDK8, affinity isolated antibody,
Reatividade de espécies
human, mouse
Aplicação
immunohistochemistry

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Olomoucine, ≥98% (HPLC),
Espécies
human, rat

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CDK8,
Espécies
human
MISSION® esiRNA, targeting mouse Cdk8,
Espécies
mouse