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Merck

CDC25B

cell division cycle 25B

Sinônimos:
Espécies:
ID UniProtKB:
ID do gene:
  • Human(994) Summary: CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]
  • Mouse(12531) cell division cycle 25B
  • Rat(171103) cell division cycle 25B
  • domestic guinea pig(100716851) cell division cycle 25B
  • naked mole-rat(101701077) cell division cycle 25B
  • cow(505847) cell division cycle 25 homolog B (S. pombe)
  • dog(485790) cell division cycle 25 homolog B (S. pombe)
  • Horse(100052425) cell division cycle 25 homolog B (S. pombe)
  • domestic cat(101092757) cell division cycle 25 homolog B (S. pombe)
  • sheep(101120511) cell division cycle 25 homolog B (S. pombe)

Custom & Knockdown Gene Products

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-CDC25B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
Anti-phospho-Cdc25b (pSer149) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
mouse
Aplicação
western blot
Anti-phospho-CDC25B (pSer323) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
Anti-phospho-CDC25B (pSer353) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry

western blot
Anti-CDC25B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot

Cell Lines

Número do produto
Descrição
Espécies
MCF10A CELLS CDC25B (-/-), ,
Espécies
human

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
NSC 95397, ≥97% (HPLC),
Espécies
human
NSC 663284, ≥98% (HPLC), solid,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human CDC25B,
Espécies
human
MISSION® esiRNA, targeting mouse Cdc25b,
Espécies
mouse