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Merck

ATP1A4

ATPase, Na+/K+ transporting, alpha 4 polypeptide

Sinônimos:
ATP1A1, ATP1AL2
Espécies:
ID UniProtKB:
ID do gene:
  • Human(480) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(27222) ATPase, Na+/K+ transporting, alpha 4 polypeptide
  • Rat(29132) ATPase, Na+/K+ transporting, alpha 4 polypeptide
  • domestic guinea pig(100729796) ATPase, Na+/K+ transporting, alpha 4 polypeptide
  • Horse(100058301) ATPase, Na+/K+ transporting, alpha 4 polypeptide
  • sheep(101118398) ATPase, Na+/K+ transporting, alpha 4 polypeptide
  • naked mole-rat(101721060) ATPase, Na+/K+ transporting, alpha 4 polypeptide
  • dog(488637) ATPase, Na+/K+ transporting, alpha 4 polypeptide
  • domestic cat(101096375) ATPase, Na+/K+ transporting, alpha 4 polypeptide
  • cow(537960) ATPase, Na+/K+ transporting, alpha 4 polypeptide

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Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
Digitoxin, ≥92% (HPLC), powder,
Espécies
human
Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
Digoxin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Espécies
human
Digoxin, European Pharmacopoeia (EP) Reference Standard,
Espécies
human
Digitoxin for LC assay, European Pharmacopoeia (EP) Reference Standard,
Espécies
human

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human ATP1A4 (2),
Espécies
human
MISSION® esiRNA, targeting human ATP1A4,
Espécies
human