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Merck

ADRA2C

adrenoceptor alpha 2C

Sinônimos:
ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
Espécies:
ID UniProtKB:
ID do gene:
  • Human(152) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11553) adrenergic receptor, alpha 2c
  • Rat(24175) adrenoceptor alpha 2C
  • domestic guinea pig(100135477) adrenergic receptor, alpha 2c
  • domestic guinea pig(101787589) adrenoceptor alpha 2C
  • cow(101902575) adrenoceptor alpha 2C
  • cow(407139) alpha-2C adrenergic receptor
  • sheep(100170319) adrenoceptor alpha 2C
  • Zebrafish(266752) adrenergic, alpha-2C-, receptor
  • chicken(428799) adrenergic, alpha-2C-, receptor
  • dog(488793) adrenoceptor alpha 2C
  • domestic cat(101087990) adrenoceptor alpha 2C
  • domestic cat(100529244) adrenoceptor alpha 2C

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Clonidine hydrochloride, solid,
Espécies
human
Xylazine hydrochloride, ≥99.0% (HPLC),
Espécies
human
Guanfacine hydrochloride, ≥98% (HPLC),
Espécies
human
Guanabenz acetate salt, powder,
Espécies
human
Tizanidine hydrochloride, ≥98% (HPLC), powder,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
Yohimbine hydrochloride, ≥98% (HPLC), powder,
Espécies
human
Idazoxan hydrochloride, ,
Espécies
human
RX 821002 hydrochloride, solid, ≥98% (HPLC),
Espécies
human
UK 14,304, ,
Espécies
human
Phentolamine hydrochloride, ≥98% (TLC), powder,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Apc antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Reatividade de espécies
human, mouse
Aplicação
immunocytochemistry
western blot
Anti-Adrenergic Receptor α-2C antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Atto 390 antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Reatividade de espécies
human, mouse
Aplicação
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Atto 488 antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Reatividade de espécies
human, mouse
Aplicação
immunocytochemistry
western blot
Monoclonal Anti-Alpha 2C Adrenergic Receptor - Rpe antibody produced in mouse, clone S330A-80, purified immunoglobulin,
Reatividade de espécies
human, mouse
Aplicação
immunocytochemistry
western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Agmatine sulfate salt, ≥97%, powder,
Espécies
human

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
UK 14,304, ,
Espécies
human
(−)-Norepinephrine, ≥98%, crystalline,
Espécies
human, rat

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting mouse Adra2c,
Espécies
mouse