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Merck

ADRA2A

adrenoceptor alpha 2A

Sinônimos:
ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
Espécies:
ID UniProtKB:
ID do gene:
  • Human(150) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11551) adrenergic receptor, alpha 2a
  • Rat(25083) adrenoceptor alpha 2A
  • domestic guinea pig(100135475) adrenergic receptor, alpha 2a
  • chicken(428980) adrenergic, alpha-2A-, receptor
  • sheep(100170317) adrenoceptor alpha 2A
  • Domestic Rabbit(100009424) adrenoceptor alpha 2A
  • Zebrafish(266750) adrenergic, alpha-2A-, receptor
  • dog(486888) adrenoceptor alpha 2A
  • domestic cat(664736) adrenoceptor alpha 2A
  • sheep(101117291) adrenoceptor alpha 2A
  • naked mole-rat(101723298) adrenoceptor alpha 2A
  • cow(282135) adrenergic, alpha-2A-, receptor

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Clonidine hydrochloride, solid,
Espécies
human
Xylazine hydrochloride, ≥99.0% (HPLC),
Espécies
human
Guanfacine hydrochloride, ≥98% (HPLC),
Espécies
human
Guanabenz acetate salt, powder,
Espécies
human
Tizanidine hydrochloride, ≥98% (HPLC), powder,
Espécies
human

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
1-Naphthylmethylamine, 97%,
Espécies
rat
Yohimbine hydrochloride, ≥98% (HPLC), powder,
Espécies
human
1,2,3,4-Tetrahydroisoquinoline, 95%,
Espécies
rat, human
Idazoxan hydrochloride, ,
Espécies
human
RX 821002 hydrochloride, solid, ≥98% (HPLC),
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Adrenergic Receptor α-2A antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ADRA2A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
canine, human, mouse, rat
Aplicação
ELISA
immunocytochemistry

immunofluorescence
Anti-ADRA2A antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
ELISA
immunofluorescence
Anti-α2A Adrenergic Receptor antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reatividade de espécies
human, mouse, pig, rat
Aplicação
immunohistochemistry
western blot

Small Molecule - Blocker

Número do produto
Descrição
Espécies
Agmatine sulfate salt, ≥97%, powder,
Espécies
human

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
UK 14,304, ,
Espécies
human
BP897, >98% (HPLC), solid,
Espécies
human, rat
(−)-Norepinephrine, ≥98%, crystalline,
Espécies
human, rat

Proteins

Número do produto
Descrição
Espécies
ChemiSCREEN Human α2A Adrenergic Receptor Membrane Preparation, Human alpha2A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Espécies
human