Skip to Content
Merck
All Photos(2)

Documents

A7791

Sigma-Aldrich

N-Acetyl-D-lactosamine

≥98% (TLC)

Synonym(s):

β-D-Gal-(1→4)-D-GlcNAc, 2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose, LN, N-Acetyl-4-O-(β-D-galactopyranosyl)-D-glucosamine

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C14H25NO11
CAS Number:
Molecular Weight:
383.35
Beilstein:
96808
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

Assay

≥98% (TLC)

form

powder

optical activity

[α]25/D 27.5 to 33.5 °, c = 0.5% (w/v) in water

technique(s)

thin layer chromatography (TLC): suitable

impurities

≤8% water

color

white

mp

170 -185  °C ((338 - 365 °F ))

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@@H]1O

InChI

1S/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12-,13?,14+/m1/s1

InChI key

KFEUJDWYNGMDBV-RPHKZZMBSA-N

Looking for similar products? Visit Product Comparison Guide

Application

N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.
Useful in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.

Preparation Note

Synthetic

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Meghan Rothenberger et al.
Journal of acquired immune deficiency syndromes (1999), 81(3), 355-360 (2019-06-14)
HIV is produced in lymphoid tissues (LT) and stored on the follicular dendritic cell network in LT. When antiretroviral therapy is started, plasma viremia decays in 2 phases; the first within days of starting therapy and the second over weeks.
Moritz Augustin et al.
PLoS computational biology, 13(6), e1005545-e1005545 (2017-06-24)
The spiking activity of single neurons can be well described by a nonlinear integrate-and-fire model that includes somatic adaptation. When exposed to fluctuating inputs sparsely coupled populations of these model neurons exhibit stochastic collective dynamics that can be effectively characterized
Paulina Sindrewicz et al.
Scientific reports, 9(1), 11851-11851 (2019-08-16)
Galectins are involved in the regulation of divergent physiological and pathological processes and are increasingly recognized to play important roles in a number of diseases. However, a simple and effective way in assessing galectin-ligand interactions is lacking. Our examination of
Fumiko Suenaga et al.
Journal of immunology (Baltimore, Md. : 1950), 194(1), 398-406 (2014-11-26)
Graft-versus-host disease (GVHD) is a major risk factor for prolonged humoral immunodeficiency and vaccine unresponsiveness after allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the underlying mechanisms for this immunodeficiency are poorly understood. In this article, we describe previously overlooked impacts
Frank Liang et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 25(12), 2635-2647 (2017-09-30)
mRNA vaccines are rapidly emerging as a powerful platform for infectious diseases because they are well tolerated, immunogenic, and scalable and are built on precise but adaptable antigen design. We show that two immunizations of modified non-replicating mRNA encoding influenza

Articles

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service