Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

19589

Sigma-Aldrich

L-2,4-Diaminobutyric acid monohydrochloride

≥98.0% (AT), ≥98.0% (TLC)

Synonym(s):

DAB

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C4H10N2O2 · HCl
CAS Number:
1482-98-0
Molecular Weight:
154.60
Beilstein:
6086583
MDL number:
MFCD01632031
UNSPSC Code:
12352200
PubChem Substance ID:
57647801

Assay

≥98.0% (AT)
≥98.0% (TLC)

form

powder or crystals

optical activity

[α]20/D +24±2°, c = 1.2% in 6 M HCl

technique(s)

ligand binding assay: suitable

color

white to off-white

mp

≥220 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Cl[H].NCC[C@H](N)C(O)=O

InChI

1S/C4H10N2O2.ClH/c5-2-1-3(6)4(7)8;/h3H,1-2,5-6H2,(H,7,8);1H/t3-;/m0./s1

InChI key

BFPDKDOFOZVSLY-DFWYDOINSA-N

Biochem/physiol Actions

L-2,4-Diaminobutyric acid (DAB) is a substrate of diaminobutyrate-pyruvate transaminase (EC 2.6.1.46), an enzyme involved in an alternative polyamine biosynthesis pathway in bacteria.
L-2,4-Diaminobutyric acid (DAB, DABA), a non-metabolized amino acid, is useful as a selective GABA uptake inhibitor which may have antitumour activity against hepatoma cells.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCBL3331V
064702/1
64702/1

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ryo Inada et al.
World journal of gastroenterology, 21(7), 2159-2168 (2015-02-27)
To analyze the mismatch repair (MMR) status and the ARID1A expression as well as their clinicopathological significance in gastric adenocarcinomas. We examined the expressions of MMR proteins and ARID1A by immunohistochemistry in consecutive 489 primary gastric adenocarcinomas. The results were
Florence Coussy et al.
International journal of cancer, 145(7), 1902-1912 (2019-03-13)
Triple-negative breast cancer (TNBC) represents 10% of all breast cancers and is a very heterogeneous disease. Globally, women with TNBC have a poor prognosis, and the development of effective targeted therapies remains a real challenge. Patient-derived xenografts (PDX) are clinically
Feng Liu et al.
Archives of gynecology and obstetrics, 300(3), 711-716 (2019-06-12)
To investigate the expression of annexin A2 (ANXA2) in ectopic and eutopic endometrium and serum of women with adenomyosis, and their relationships with adenomyosis-associated dysmenorrhea. The expression of ANXA2 was detected by immunohistochemical S-P method in ectopic and eutopic endometrium
Mei-Ling Chen et al.
Medicina (Kaunas, Lithuania), 55(7) (2019-07-10)
Prostate cancer (PCa) is a common malignancy in males and has a relatively slower progression than other cancers. Our goal was to evaluate the clinical role of SPARC (secreted protein acidic and cysteine rich, osteonectin), cwcv, and kazal-like domains' proteoglycan
Mirko Manetti et al.
Journal of clinical medicine, 8(7) (2019-07-03)
Hemophilic arthropathy (HA) typically begins with proliferative synovitis that shares some similarities with inflammatory arthritides, in which the proinflammatory cytokine tumor necrosis factor (TNF)-α has a crucial pathogenetic role. Inappropriate release of TNF-α was shown to contribute to arthropathy development
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service