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SMB01365

Sigma-Aldrich

3-Fucosyllactose

≥95% (HPLC)

Synonym(s):

3-O-α-L-Fucopyranosyllactose, 3-O-α-L-Fucosyllactose

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About This Item

Empirical Formula (Hill Notation):
C18H32O15
CAS Number:
41312-47-4
Molecular Weight:
488.44
UNSPSC Code:
12352201
NACRES:
NA.51

Quality Level

100

Assay

≥95% (HPLC)

form

solid

shipped in

wet ice

storage temp.

−20°C

InChI

1S/C18H32O15/c1-4-7(21)9(23)11(25)17(29-4)33-15-13(27)16(28)30-6(3-20)14(15)32-18-12(26)10(24)8(22)5(2-19)31-18/h4-28H,2-3H2,1H3/t4-,5+,6+,7+,8-,9+,10-,11-,12+,13+,14+,15+,16?,17-,18-/m0/s1

InChI key

WJPIUUDKRHCAEL-YVEAQFMBSA-N

General description

Human milk and colostrum contain some 200 different HMOs (human milk oligosaccharides). They are formed of combinations of glucose, N-acetylglucosamine, galactose (Gal), fucose (Fuc), and N-acetylneuraminic acid (sialic acid), with a lactose unit at the reducing end. HMOs are of great interest for baby formula production and as potential drug treatments for adult diseases. 3-Fucosyllactose is a neutral HMO. Similarly to other HMOs, 3-fucosyllactose is not digested by humans and acts as a prebiotic, which facilitates the growth of healthy bacteria in the gut.

Application

Metabolomics research
Microbiome research

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000357809
0000357809
SLCN4655

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Eva M Moya-Gonzálvez et al.
Scientific reports, 11(1), 23328-23328 (2021-12-04)
Much evidence suggests a role for human milk oligosaccharides (HMOs) in establishing the infant microbiota in the large intestine, but the response of particular bacteria to individual HMOs is not well known. Here twelve bacterial strains belonging to the genera
Chunli Kong et al.
Food & function, 12(24), 12513-12525 (2021-11-24)
Human milk oligosaccharides (hMOs) are unique bioactive components in human milk. 3-Fucosyllactose (3-FL) is an abundantly present hMO that can be produced in sufficient amounts to allow application in infant formula. Lacto-N-triaose II (LNT2) can be obtained by acid hydrolysis
Krista Salli et al.
Journal of agricultural and food chemistry, 69(1), 170-182 (2021-01-01)
Prebiotic human milk oligosaccharides (HMOs) are found in human milk, which are not digested by infants but are metabolized by beneficial gut bacteria. We determined the ability of 57 bacterial strains within the Family Lactobacillaceae and genera Bifidobacterium and Bacteroides

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