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About This Item
Empirical Formula (Hill Notation):
C12H14N2O2 · HCl
CAS Number:
Molecular Weight:
254.71
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
optical activity
[α]20/D −18°, c = 5 in methanol
reaction suitability
reaction type: solution phase peptide synthesis
mp
213-216 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl.COC(=O)[C@H](N)Cc1c[nH]c2ccccc12
InChI
1S/C12H14N2O2.ClH/c1-16-12(15)10(13)6-8-7-14-11-5-3-2-4-9(8)11;/h2-5,7,10,14H,6,13H2,1H3;1H/t10-;/m1./s1
InChI key
XNFNGGQRDXFYMM-HNCPQSOCSA-N
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Massoud Akhtari et al.
Epilepsia, 49(8), 1419-1430 (2008-05-16)
The development of nonradioactive and targeted magnetonanoparticles (MNP) capable of crossing the blood-brain barrier (BBB) and of concentrating in the epileptogenic tissues of acute and chronic animal models of temporal lobe epilepsy to render these tissues visible on magnetic resonance
Patrick P C Boor et al.
European journal of immunology, 41(6), 1663-1674 (2011-04-07)
Allo-reactive memory T cells are a major barrier for induction of immunological tolerance to allografts in humans. Here, we report that stimulation of unfractionated human T cells with TLR-stimulated allogeneic plasmacytoid dendritic cells (pDCs) induces CD8(+) regulatory T cells (Tregs)
Vijay Narayan Tiwari et al.
Journal of child neurology, 27(5), 598-603 (2011-12-06)
In this study, we determined whether diffusion tensor imaging (DTI), a more widely available imaging modality, is as effective as α-[(11)C]methyl-l-tryptophan (AMT)-positron emission tomography (PET) in localizing epileptogenic tubers in tuberous sclerosis complex. Following that, coregistration of AMT-PET and diffusion
E D Vasil'eva et al.
Bulletin of experimental biology and medicine, 149(5), 625-627 (2010-12-18)
We studied the effect of 1-methyl-D-tryptophan, an inhibitor of indoleamine-2,3-dioxygenase, on the growth of transplanted hepatocarcinoma-29 in C3HA mice. Hepatocarcinoma-29 transplanted into the thigh muscles undergoes immunological rejection in more than 50% non-syngeneic recipients. Chronic local administration of 1-methyl-D-tryptophan promotes
Kanishka Mohib et al.
American journal of physiology. Renal physiology, 295(1), F226-F234 (2008-05-16)
Indoleamine 2,3-dioxygenase (IDO) catabolizes tryptophan to N-formyl kynurenine and has a proapoptotic role in renal tubular epithelial cells (TEC) in response to IFN-gamma and TNF-alpha in vitro. TEC produce abundant amounts of IDO in vitro in response to inflammation but
Chromatograms
application for HPLCActive Filters
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