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453161

Sigma-Aldrich

Manganese(III) 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine chloride tetrakis(methochloride)

Dye content 85 %

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About This Item

Empirical Formula (Hill Notation):
C44H36Cl5MnN8
CAS Number:
Molecular Weight:
909.01
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23

form

solid

Quality Level

composition

Dye content, 85%

mp

>300 °C (lit.)

λmax

462 nm

SMILES string

CCl.CCl.CCl.CCl.Cl[Mn]1n2c3ccc2c(-c4ccncc4)c5ccc(n5)c(-c6ccncc6)c7ccc(c(-c8ccncc8)c9ccc(n9)c3-c%10ccncc%10)n17

InChI

1S/C40H24N8.4CH3Cl.ClH.Mn/c1-2-30-38(26-11-19-42-20-12-26)32-5-6-34(47-32)40(28-15-23-44-24-16-28)36-8-7-35(48-36)39(27-13-21-43-22-14-27)33-4-3-31(46-33)37(29(1)45-30)25-9-17-41-18-10-25;4*1-2;;/h1-24H;4*1H3;1H;/q-2;;;;;;+3/p-1/b37-29-,37-31-,38-30-,38-32-,39-33-,39-35-,40-34-,40-36-;;;;;;

InChI key

ZSSLGZVVWLRLKL-ZUMCYRATSA-M

General description

Manganese(III) 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine chloride tetrakis(methochloride) (MnTMPyP )is a mitochondrial superoxide dismutase (SOD) mimetic agent.

Application

MnTMPyP was used as a mitochondrial superoxide dismutase mimetic agent in a study to understand the ability of mitochondrial superoxide anion radicals to mediate glutamate-induced oxidative DNA damage.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease
2. Yang JL, et al.
The Journal of Biological Chemistry, 285(36), 28191-28199 (2010)
Novel high-throughput assay for antioxidant capacity against superoxide anion.
Zhang L, et al.
Journal of Agricultural and Food Chemistry, 57(7), 2661-2667 (2009)

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