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T9573

Sigma-Aldrich

Anti-phospho-Tyrosine Hydroxylase (pSer40) antibody produced in rabbit

affinity isolated antibody, aqueous glycerol solution, sufficient for 10 blots

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

aqueous glycerol solution

Utilisation

sufficient for 10 blots

Poids mol.

antigen 60 kDa

Espèces réactives

rat, mouse, human

Technique(s)

immunohistochemistry: 1:1000
western blot: 1:1000 using lysates of PC-12 Cells stimulated by Okadaic Acid (1 μM for 60 minutes)

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

phosphorylation (pSer40)

Informations sur le gène

human ... TH(7054)
mouse ... Th(21823)
rat ... Th(25085)

Spécificité

Specifically recognizes tyrosine hydroxylase phosphorylated at serine 40.

Immunogène

synthetic phosphorylated peptide corresponding to amino acids residues surrounding the rat TH phosphorylated on serine 40.

Forme physique

Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/ml BSA and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pictogrammes

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Mention d'avertissement

Warning

Mentions de danger

Conseils de prudence

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Exposure to high-intensity or outdoor lighting has been shown to decrease the severity of myopia in both human epidemiological studies and animal models. Currently, it is not fully understood how light interacts with visual signaling to impact myopia. Previous work
Alán Alpár et al.
The EMBO journal, 37(21) (2018-09-14)
Stress-induced cortical alertness is maintained by a heightened excitability of noradrenergic neurons innervating, notably, the prefrontal cortex. However, neither the signaling axis linking hypothalamic activation to delayed and lasting noradrenergic excitability nor the molecular cascade gating noradrenaline synthesis is defined.
Scot McIntosh et al.
Frontiers in psychiatry, 4, 88-88 (2013-08-24)
Chronic cocaine administration regulates the expression of several proteins related to dopaminergic signaling and synaptic function in the mesocorticolimbic pathway, including the prefrontal cortex. Functional abnormalities in the prefrontal cortex are hypothesized to be due in part to the expression
András H Lékó et al.
Scientific reports, 7(1), 3396-3396 (2017-06-15)
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