T8806

Thymopentin

≥97% (HPLC)

• Synonyme(s) : TP5, Arg-Lys-Asp-Val-Tyr
• Formule empirique (notation de Hill): C₃₀H₄₉N₉O₉
• Numéro CAS: 69558-55-0
• Poids moléculaire : 679.76
• Numéro MDL: MFCD00214200
• Code UNSPSC : 12352209
• ID de substance PubChem : 329826886
• Nomenclature NACRES : NA.26

Propriétés

• product name: Thymopentin, ≥97% (HPLC)
• Niveau de qualité: 200
• Pureté: ≥97% (HPLC)
• Forme: powder
• Couleur: white
• Application(s): cell analysis
• Température de stockage: −20°C
• Chaîne SMILES: CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
• InChI: 1S/C30H49N9O9/c1-16(2)24(28(46)38-22(29(47)48)14-17-8-10-18(40)11-9-17)39-27(45)21(15-23(41)42)37-26(44)20(7-3-4-12-31)36-25(43)19(32)6-5-13-35-30(33)34/h8-11,16,19-22,24,40H,3-7,12-15,31-32H2,1-2H3,(H,36,43)(H,37,44)(H,38,46)(H,39,45)(H,41,42)(H,47,48)(H4,33,34,35)/t19-,20-,21-,22-,24-/m0/s1
• Clé InChI: PSWFFKRAVBDQEG-YGQNSOCVSA-N

Description

Amino Acid Sequence

Arg-Lys-Asp-Val-Tyr

Description générale

Thymopentin (TP5) is a pentapeptide produced by the epithelial cells of the thymic cortex and medulla. It consists of thymosin α1 (Tα1).

Actions biochimiques/physiologiques

Thymopentin (TP5) is an immunomodulator, resembling the active site of the thymopoietin. TP5 stimulates cellular immune responses such as T-cell formation, natural killer (NK) cell and macrophage activation, generation of cytokines, and activation of B-cell for antibody production. It also mimics the polypeptide environment of the thymus. TP5 is used to treat conditions like immune deficiency, autoimmune diseases, infections, and cancers. It has a short half-life and is rapidly metabolized in the gastrointestinal tract.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)