SRP8026
Annexin V human
recombinant, expressed in E. coli, GST tagged, ≥95% (SDS-PAGE)
Synonyme(s) :
Annexin A5, Calphobindin I, EC 2.7.1.23, Endonexin II, Placental anticoagulantprotein I
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About This Item
Code UNSPSC :
12352200
Nomenclature NACRES :
NA.32
Produits recommandés
Source biologique
human
Produit recombinant
expressed in E. coli
Étiquette/Marqueur
GST tagged
Pureté
≥95% (SDS-PAGE)
Forme
lyophilized
Poids mol.
~52 kDa
Conditionnement
pkg of 100 μg
Conditions de stockage
avoid repeated freeze/thaw cycles
Technique(s)
activity assay: suitable
Couleur
white
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Température de stockage
−20°C
Informations sur le gène
human ... ANXA5(308)
Description générale
Annexin V is a member of the annexin family of calcium and membrane-binding proteins that have anticoagulatory and anti-inflammatory properties. The encoded protein is 320 amino acid long and is folded into four domains, each having five α-helices, forming a superhelical globular structure. The ANX5 gene is mapped to human chromosome 4q26-q28 and spans a length of 28kb containing 13 exons and 12 introns.
Application
Annexin V has been used to examine phosphorylation activity of ChaK1 (channel-kinase 1).
Actions biochimiques/physiologiques
Annexins are a family of water-soluble proteins that bind to membranes and phospholipids in a calcium-dependent manner. They participate in several cellular functions, such as membrane fusion and cytoskeletal interaction. Annexin V is a potent anticoagulant and serves as a voltage-gated calcium channel when bound to membrane in vitro. It is found to inhibit phospholipase A2 and protein kinase C.
Forme physique
Lyophilized from PBS, pH 7.4.
Reconstitution
Reconstitute with 100 μL deionized water.
Autres remarques
Recombinant human annexin V fused to a GST-tag.
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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