The Positive Control functions as a system control to verify the functionality of the kit components. The resulting OD will not be utilized in any calculations. Any signal within the standard curve range that demonstrates competition in the assay indicates that the assay is performing as anticipated.
RAB0010
Angiotensin II EIA Kit
for serum, plasma, culture supernatant and cell lysates
Synonyme(s) :
Angiotensinogen, Serpin A8
Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Sélectionner une taille de conditionnement
1 KIT
500,00 €
500,00 €
Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.
Sélectionner une taille de conditionnement
Changer de vue
1 KIT
500,00 €
About This Item
Code UNSPSC :
12352204
Nomenclature NACRES :
NA.32
500,00 €
Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.
Produits recommandés
Espèces réactives
mouse, human, rat
Conditionnement
kit of 96 wells (12 strips x 8 wells)
Technique(s)
ELISA: suitable
enzyme immunoassay: suitable
Entrée
sample type cell lysate
sample type culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 2.62 pg/mL
standard curve range: 0.1-1000 ng/mL
Méthode de détection
colorimetric
Conditions d'expédition
wet ice
Température de stockage
−20°C
Informations sur le gène
human ... AGT(183)
Catégories apparentées
Description générale
The Angiotensin II Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting Angiotensin II peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANGII-1 can theoretically detect all active angiotensins, including ANGI, ANGII, ANGIII and ANGIV. However, it does not detect inactive angiotensinogen.
Immunogène
Angiotensin II, synthetic peptide
Application
For research use only. Not for use in diagnostic procedures.
Angiotensin II EIA Kit has been used for analyzing circulating and serum levels of angiotensin II (Ang II) in mice and rats respectively.[3][1]
Angiotensin II EIA Kit has been used for analyzing circulating and serum levels of angiotensin II (Ang II) in mice and rats respectively.[3][1]
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Actions biochimiques/physiologiques
Study on in vitro model shows that mechanical stretch induced Ang II release plays a vital role in mediating stretch-induced hypertrophic response.[4] Ang II is implicated in maintaining blood pressure and has an important role in hypertension and in the pathophysiology of cardiovascular disorders. Ang II also has an essential role in growth induction, cell migration and mitosis of vascular smooth muscle cells. It enhances the production of collagen type I and III in fibroblasts, that results in thickening of the vascular wall and myocardium, and fibrosis. Variation in Ang II gene increases the risk of myocardial infarction, hypertension and left ventricular hypertrophy.[5] Ang II expression is associated with heart failure, cardiac remodeling, diabetes, and the proliferative and inflammatory responses to arterial injury. The pharmacological agents such as angiotensin II-converting enzyme inhibitors or angiotensin II receptor antagonists can be used for treating Ang II-induced hypertension and congestive heart failure.[6]
Composants de kit également disponibles séparément
Réf. du produit
Description
FDS
- RABHRP3HRP-StreptavidinFDS
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Met. Corr. 1
Code de la classe de stockage
8A - Combustible corrosive hazardous materials
Faites votre choix parmi les versions les plus récentes :
Certificats d'analyse (COA)
Lot/Batch Number
Vous ne trouvez pas la bonne version ?
Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Les clients ont également consulté
Role of angiotensin II in blood pressure regulation and in the pathophysiology of cardiovascular disorders.
Fyhrquist F
Journal of Human Hypertension, 9 suppl 5, S19-S24 (1995)
Daniela Volonte et al.
The Journal of biological chemistry, 296, 100242-100242 (2021-01-01)
Oncogenic K-Ras (K-RasG12V) promotes senescence in normal cells but fuels transformation of cancer cells after the senescence barrier is bypassed. The mechanisms regulating this pleiotropic function of K-Ras remain to be fully established and bear high pathological significance. We find
Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension.
Yang T
Journal of the American Heart Association, 5(7) (2016)
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro.
Sadoshima J
Cell, 75(5), 977-984 (1993)
Genetic abrogation of adenosine A3 receptor prevents uninephrectomy and high salt-induced hypertension
Yang T, et al.
Journal of the American Heart Association, 5(7), e003868-e003868 (2016)
-
What is the expected response for the positive control in the Human Angiotensin II EIA (RAB0010)?
1 answer-
Helpful?
-
Active Filters
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique
