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N8000

Sigma-Aldrich

1-Naphthyl butyrate

esterase substrate, ≥99% (GC), liquid

Synonyme(s) :

Butanoic acid 1-naphthyl ester, Butyric acid 1-naphthyl ester

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About This Item

Formule linéaire :
CH3CH2CH2CO2C10H7
Numéro CAS:
3121-70-8
Poids moléculaire :
214.26
Numéro Beilstein :
2558646
Numéro CE :
221-500-7
Numéro MDL:
MFCD00003923
Code UNSPSC :
12352204
ID de substance PubChem :
24897845
Nomenclature NACRES :
NA.32

product name

1-Naphthyl butyrate, esterase substrate

Description

esterase substrate

Pureté

≥99% (GC)

Forme

liquid

Indice de réfraction

n20/D 1.571 (lit.)

Point d'ébullition

125-130 °C/1 mmHg (lit.)

Solubilité

ethanol: 100 mg/mL, clear, colorless to faintly yellow

Densité

1.091 g/mL at 20 °C (lit.)

Température de stockage

−20°C

Chaîne SMILES 

CCCC(=O)Oc1cccc2ccccc12

InChI

1S/C14H14O2/c1-2-6-14(15)16-13-10-5-8-11-7-3-4-9-12(11)13/h3-5,7-10H,2,6H2,1H3

Clé InChI

XIVJNRXPRQKFRZ-UHFFFAOYSA-N

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Application

1-Naphthyl butyrate has been used as a substrate for esterase activity in sheep body louse Bovicola ovis and in chromogenic staining of flounder fish samples.

Actions biochimiques/physiologiques

1-Naphthyl butyrate also called α-naphthyl butyrate is a substrate for esterase enzyme. α-naphthyl butyrate aids in assessing α-naphthyl butyrate esterase activity in monocytes and lymphocytes.

Substrats

Esterase substrate.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

143.6 °F - closed cup

Point d'éclair (°C)

62 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

J Yourno et al.
Blood, 60(1), 24-29 (1982-07-01)
Lymphocytes from a case of B-cell chronic lymphocytic leukemia (CLL) were obtained in a highly purified state from a therapeutic leukapheresis preparation. The CLL lymphocytes showed a fine, scattered, granular pattern of nonspecific esterase cytochemical reactivity with either alpha-naphthyl acetate
Y Kaneko et al.
Blood, 60(2), 389-399 (1982-08-01)
We studied the karyotype in 26 children with ANLL, which was diagnosed on the basis of the FAB classification. Clonal chromosome abnormalities were found in 21 of 26 patients. Four patients, including 3 with Down's syndrome, had AML(M1). Nine patients
P M Mattes et al.
Toxicology and applied pharmacology, 114(1), 71-76 (1992-05-01)
Carboxylesterase activity in the rat nasal mucosa plays an important role in the response of this tissue to certain toxic inhaled esters. We have examined this activity in extracts of both Fischer-344 rat and human nasal tissue using the substrate
J Yourno et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 34(6), 727-733 (1986-06-01)
Monocytes contain a characteristic, prominent set of membrane-bound nonspecific esterases with a slightly acid isoelectric point. These esterases are also detected at modest levels in some granulocyte preparations. They are not apparent in lymphocytes. Among 18 fresh myeloid leukemias and
T Honda et al.
Histochemistry, 77(3), 299-302 (1983-01-01)
The proteases of human leukocytes were cytochemically studied by use of new alpha-naphthyl esters, tosyl-L-lysine-alpha-naphthyl ester (TLNE) and acetyl-L-tyrosine-alpha-naphthyl ester (ATNE). The hydrolytic activities were strong only in neutrophils, with both substrates. They were inhibited completely by DFP and chymostatin
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