MAK265
Fructose Colorimetric/Fluorometric Assay Kit
sufficient for 100 colorimetric or fluorometric tests
Synonyme(s) :
Fructose Detection Kit
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About This Item
Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84
Produits recommandés
Méthode de détection
colorimetric
fluorometric
Température de stockage
−20°C
Description générale
Fructose is a monosaccharide naturally found in honey and fruits. Several studies have linked fructose to the development of the metabolic syndrome particularly through promoting insulin resistance in the liver. It has also been implicated in the obesity epidemic. Studies in animals have revealed high fructose intake during pregnancy and lactation may lead to metabolic dysfunctions in the mother and the newborn. Fructose measurements can provide useful insights into metabolic and biochemical functions. Excessive uptake of fructose is implicated in obesity in children. Fructose induced hyperuricemia, reduces nitric oxide bioavailability for insulin and thus it is implicated in diabetes. Fructose might be implicated in cardiovascular disease, as it is the only sugar that raises uric acid production in the body. High fructose diet is known to induce hypertension.
Caractéristiques et avantages
Compatible with high-throughput handling systems.
Adéquation
Suitable for detecting fructose in cell and tissue culture supernatants. Note: Not suitable for urine, plasma, or serum.
Principe
In this assay kit, fructose is converted to -glucose resulting in a colorimetric (570 nm)/fluorometric (ex = 535 nm/em = 587 nm) product proportional to fructose present. This kit has a linear range of detection between 0.2–1.0 nmole fructose for the fluorometric assay and 2–10 nmole fructose for the colorimetric assay.
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Aquatic Chronic 3 - Resp. Sens. 1 - Skin Sens. 1
Code de la classe de stockage
10 - Combustible liquids
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
A causal role for uric acid in fructose-induced metabolic syndrome.
Nakagawa T, et al.
American Journal of Physiology: Renal Physiology, 290(3), F625-F631 (2006)
Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease.
Johnson R J, et al.
American Journal of Clinical Nutrition, 86(4), 899-906 (2007)
Nattawan Suwannakul et al.
Genes & diseases, 9(6), 1727-1741 (2022-09-27)
Alterations in cellular metabolism may contribute to tumor proliferation and survival. Upregulation of the facilitative glucose transporter (GLUT) plays a key role in promoting cancer. GLUT5 mediates modulation of fructose utilization, and its overexpression has been associated with poor prognosis
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