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M9555

Sigma-Aldrich

Anti-Matrix Metalloproteinase-9 antibody produced in rabbit

1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

Synonyme(s) :

Anti-MMP-9

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About This Item

Numéro MDL:
Code UNSPSC :
12352203

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Clone

polyclonal

Forme

buffered aqueous glycerol solution

Poids mol.

antigen (active form) 88 kDa
antigen (pro-form) 92 kDa

Espèces réactives

human, mouse

Concentration

1 mg/mL

Technique(s)

immunohistochemistry (frozen sections): suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 1:1,000

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... MMP9(4318)
mouse ... Mmp9(17395)

Spécificité

Reacts with reduced and native MMP-9. The antibody recognizes pro-form and active forms of MMP-9. Mouse MMP-9 is slightly larger than human MMP-9.

Immunogène

corresponding to intact mouse matrix metalloproteinase-9 (gelatinase-B).

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry-paraffin (1 paper)
Western Blotting (1 paper)

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.

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Simon Jönsson et al.
PloS one, 9(8), e105572-e105572 (2014-08-26)
Matrix metalloproteinase (MMP)-9 may play a central role in the development and progression of atherosclerosis. Emerging evidence also indicates an association between MMP-9 and depressive symptomatology. Here, we investigated whether expression of MMP-9 and its inhibitors in blood mononuclear cells
Pei-Chan Zheng et al.
Cancer science, 105(6), 630-638 (2014-04-08)
Calpain small subunit 1 (Capn4) plays a key role in tumor migration or invasion. In this study, expression and function of Capn4 was investigated in human nasopharyngeal carcinoma (NPC). Here we report that both mRNA and protein levels of Capn4
Guo-Cai Li et al.
Cancer science, 101(12), 2546-2553 (2010-10-15)
The effects of mesenchymal stem cells (MSC) on the growth and metastasis of human malignancies including hepatocellular carcinoma (HCC) are controversial, and the underlying mechanisms are not yet understood. The aim of this study was to explore the role of
Heiani Touaitahuata et al.
Developmental biology, 393(1), 57-70 (2014-07-06)
During long bone development and post-natal growth, the cartilaginous model of the skeleton is progressively replaced by bone, a process known as endochondral ossification. In the primary spongiosa, osteoclasts degrade the mineralized cartilage produced by hypertrophic chondrocytes to generate cartilage
Spencer Slavin et al.
Carcinogenesis, 35(6), 1301-1309 (2014-01-01)
The prostate cancer (PCa) microenvironment contains active stromal cells known as cancer-associated fibroblasts (CAF) that may play important roles in influencing tumor progression. Here we studied the role of CAF estrogen receptor alpha (ERα) and found that it could protect

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