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M4773

Sigma-Aldrich

Metaraminol (+)-bitartrate salt

Synonyme(s) :

(−)-m-Hydroxyphenylpropanolamine bitartrate salt

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About This Item

Formule empirique (notation de Hill):
C9H13NO2 · C4H6O6
Numéro CAS:
33402-03-8
Poids moléculaire :
317.29
Numéro CE :
251-502-3
Numéro MDL:
MFCD00238763
Code UNSPSC :
12352200
ID de substance PubChem :
24896944
Nomenclature NACRES :
NA.77

Auteur

Merck & Co., Inc., Kenilworth, NJ, U.S.

Chaîne SMILES 

O[C@H]([C@@H](O)C(O)=O)C(O)=O.C[C@H](N)[C@H](O)c1cccc(O)c1

InChI

1S/C9H13NO2.C4H6O6/c1-6(10)9(12)7-3-2-4-8(11)5-7;5-1(3(7)8)2(6)4(9)10/h2-6,9,11-12H,10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t6-,9-;1-,2-/m01/s1

Clé InChI

VENXSELNXQXCNT-IJYXXVHRSA-N

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Application

Metaraminol (+)-bitartrate salt has been used to study the effects of adrenergic agonists in the mouse model of endometriosis.

Actions biochimiques/physiologiques

α-adrenoceptor agonist.
Metaraminol may serve as a false sympathetic transmitter. It is a mixed α - and β-adrenergic agonist.

Caractéristiques et avantages

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H301 + H311 + H331

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

T P Haydon et al.
Anaesthesia and intensive care, 36(5), 736-738 (2008-10-16)
We report the case of a 51-year-old woman receiving endobronchial treatment with neodymium:yttrium garnet laser After 30 minutes of stable anaesthesia and laser treatment, sudden inferior myocardial ischaemia developed followed by haemodynamic collapse. Resuscitation with fluids, pressors, atropine and esmolol
Ying Huang et al.
Se pu = Chinese journal of chromatography, 28(11), 1084-1088 (2011-03-09)
A method for the determination of three adrenergic drugs, including phenylephrine hydrochloride (PHE), metaraminol bitartrate (MR) and isoprenaline hydrochloride (IP), was developed using capillary electrophoresis with amperometric detection. The detection potential of working electrode was 0.950 V versus the reference
S Y Yeh
Physiology & behavior, 68(1-2), 227-234 (2000-01-08)
Structure-anorectic activity relationship of two substituted amphetamines has been investigated in this study. Literature reports showed conflicting results in their anorectic activities in spite of the similarity in chemical structures of metaraminol and phenylephrine. Hence, the effects of alpha-carbon atom
T D Phan et al.
Anaesthesia and intensive care, 39(6), 1014-1021 (2011-12-15)
This study compared the cardiac output responses to haemodynamic interventions as measured by three minimally invasive monitors (Oesophageal Doppler Monitor the VigileoFlotrac and the LiDCOrapid) to the responses measured concurrently using thermodilution, in cardiac surgical patients. The study also assessed
E T Yamaguchi et al.
International journal of obstetric anesthesia, 20(3), 224-228 (2011-06-07)
The aim of this study was to determine serum oxytocin concentrations following different regimens of prophylactic oxytocin administration in women undergoing elective caesarean delivery. Thirty healthy pregnant patients were randomized, after clamping of the umbilical cord, to receive intravenous oxytocin
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