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GW21213

Sigma-Aldrich

Anti-KCMF1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Anti-Hypothetical protein KCMF1, Anti-PCMF, Anti-Potassium channel modulatory factor

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

chicken

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

human

Fabricant/nom de marque

Genway 15-288-21213

Technique(s)

western blot: suitable

Numéro d'accès NCBI

NP_064507.1

Numéro d'accès UniProt

Q4ZG04

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... KCMF1(56888)

Immunogène

Immunogen Sequence: GI # 10047128, sequence 280-375
Recombinant potassium channel modulatory factor

Application

Anti-KCMF1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Actions biochimiques/physiologiques

KCMF1 (DEBT91) is mapped to chromosome 2p11.2 in humans. It encodes a 381 amino acid molecule with high Ser and Thr composition and is highly conserved at its N-terminus across species. DEBT91 is suggested to be a coiled-coil nuclear phosphoprotein with zinc finger motifs at the N-terminal conserved region, which is rich in cysteine and histidine. It is an immediate early gene up-regulated during growth factor-induced branching tubulogenesis. DEBT91 plays an important role in gastric carcinogenesis. Its upregulation in response to bFGF in gastric cancer might be implicated in carcinogenesis through dysregulation of growth modulator.

Forme physique

Solution in phosphate buffered saline containing 0.02% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

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Jun-Hyeog Jang
FEBS letters, 578(1-2), 21-25 (2004-12-08)
We have previously shown that fibroblast growth factor receptor 2 (FGFR2) plays an important role in gastric carcinogenesis. In this study, we have used a differential display approach to identify basic fibroblast growth factor (bFGF)-inducible genes in gastric cancer cells.
Zhixing Li et al.
Biochemical and biophysical research communications, 306(3), 623-628 (2003-06-18)
In a differential screen for genes that might be important in the regulation of epithelial morphogenesis, we identified a novel gene, Debt91 (differentially expressed in branching tubulogenesis), which is up-regulated in an in vitro model of renal tubulogenesis and branching.

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