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D3196

Dipeptidyl Peptidase VIII human

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10 μg
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674,00 €

A propos de cet article

NACRES:
NA.54
UNSPSC Code:
12352204
Specific activity:
≥20 units/μg protein
Recombinant:
expressed in Sf9 cells
Concentration:
≥0.08 mg/mL

674,00 €


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Quality Segment

recombinant

expressed in Sf9 cells

form

solution

specific activity

≥20 units/μg protein

mol wt

100 kDa

concentration

≥0.08 mg/mL

shipped in

dry ice

storage temp.

−70°C

General description

Full length sequence with an N-terminal GST tag

Application

Human dipeptidyl peptidase VIII has been used in a study to identify ERGIC-53 as an intracellular transport receptor of α1-antitrypsin. Human dipeptidyl peptidase VIII has also been used in a study to investigate the cargo selectivity of the ERGIC-53/MCFD2 transport receptor complex.

Biochem/physiol Actions

Dipeptidyl peptidase VIII (DPP8) is a 100 kDa monomeric protein expressed in the cytoplasm. It is a postproline dipeptidyl aminopeptidase that is homologous to DPPIV and fibroblast activation protein (FAP). It hydrolyzes Ala-Pro, Arg-Pro and Gly-Pro. DPP8 has a neutral pH optimum. It may be involved in T-cell activation and immune function as it is similar to DPPIV . It is upregulated during immune activation.[1]

Physical form

Supplied as a solution in 40 mM Tris-HCL, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT and 20% glycerol.

Other Notes

One unit will hydrolyze 1.0 picomole of Ala-Pro-AMC per minute at pH 7.4 at 25 deg °C

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Cet article
D3071D3321D3571
specific activity

≥20 units/μg protein

specific activity

≥250 units/μg protein

specific activity

≥1,500 units/μg protein, ≥1500 units/μg protein

specific activity

≥400 units/μg protein

recombinant

expressed in Sf9 cells

recombinant

expressed in Sf9 cells

recombinant

expressed in Sf9 cells

recombinant

expressed in Sf9 cells

concentration

≥0.08 mg/mL

concentration

-

concentration

-

concentration

≥0.1 mg/mL

form

solution

form

solution

form

solution

form

solution

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

mol wt

100 kDa

mol wt

-

mol wt

89.1 kDa

mol wt

82 kDa


Classe de stockage

10 - Combustible liquids

wgk

WGK 1



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Questions

1–2 of 2 Questions  
  1. What is the molecular weight of Product D3196, Dipeptidyl Peptidase VIII human?

    1 answer
    1. The molecular weight of Product D3196, Dipeptidyl Peptidase VIII human with N-terminal GST tag, is 129.3 kDa.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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