D2625

Dansyl chloride

BioReagent, suitable for amino acid labeling, powder and chunks, ≥99% (HPLC)

• Synonyme(s) : 5-(Dimethylamino)naphthalene-1-sulfonyl chloride, DNSCl
• Formule empirique (notation de Hill): C₁₂H₁₂ClNO₂S
• Numéro CAS: 605-65-2
• Poids moléculaire : 269.75
• Numéro Beilstein : 2217205
• Numéro CE : 210-092-6
• Numéro MDL: MFCD00003985
• Code UNSPSC : 12352101
• ID de substance PubChem : 24893700
• Nomenclature NACRES : NA.26

Propriétés

• Gamme de produits: BioReagent
• Pureté: ≥99% (HPLC)
• Forme: powder and chunks
• Couleur: yellow to yellow-orange
• Pf: 72-74 °C (lit.)
• Solubilité: acetone: 20 mg/mL
• Adéquation: suitable for amino acid labeling
• Température de stockage: 2-8°C
• Chaîne SMILES: CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
• InChI: 1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
• Clé InChI: XPDXVDYUQZHFPV-UHFFFAOYSA-N

Description

Application

Dansyl chloride has been used:

• as a fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase high performance liquid chromatography (HPLC)
• in the derivatization of plasma samples
• in the quantification of immobilized alkaline phosphatase

A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.

Actions biochimiques/physiologiques

Dansyl chloride is a sulfonyl chloride compound. It is used to end tag amino groups of peptides and proteins. Dansyl chloride is used for derivatization of free amino acids and amines in neural samples and biological fluids. It is used to study fluorescent conjugates of albumin, protein conformational changes studies and active site characterization.

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H290,H314
• Conseils de prudence: P234 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Code de la classe de stockage: 8A - Combustible corrosive hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges