A4095

Anti-phospho-ATF-2 (pThr^69,71) antibody, Mouse monoclonal

clone ATF-22P, purified from hybridoma cell culture

• Synonyme(s) : Monoclonal Anti-phospho-ATF-2 (pThr^69,71)
• Numéro MDL: MFCD03096614
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: ATF-22P, monoclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 60-70 kDa (triplet)
• Espèces réactives: frog, mouse, rat, chicken, human
• Concentration: 0.5-1.0 mg/mL
• Technique(s): immunocytochemistry: suitable; indirect ELISA: suitable; microarray: suitable; western blot: suitable
• Isotype: IgG1
• Numéro d'accès UniProt: P15336
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pThr69/pThr71)
• Informations sur le gène: human ... ATF2(1386) ; mouse ... Atf2(11909) ; rat ... Atf2(81647)

Description

Description générale

ATF2 (Activating Transcription Factor 2) is a member of the leucine zipper family of transcription factors. It binds to CRE domains and stimulates CRE-dependent transcription.

Mouse monoclonal anti-phospho-ATF-2 (pThr^69,71) reacts specifically with ATF2 phosphorylated at both threonine 69 and 71, and does not detect the monophosphorylated and the non-phosphorylated ATF2 molecule. The epitope recognized by the antibody resides in the N-terminal region of ATF2 (aa 66-79, pT^69,71). This epitope is identical in ATF2 of human, rat, mouse, chicken and frog. The antibody cross-reacts with human, rat and mouse ATF2.

Immunogène

synthetic peptide corresponding to the N-terminal amino acids 66-79 (pT^69,71) of human ATF2. This sequence is identical in ATF2 from human, rat, mouse, chicken, and frog.

Application

Mouse monoclonal anti-phospho-ATF-2 (pThr^69,71) antibody can be used for immunocytochemistry, indirect ELISA, microarray, and western blot.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Notes préparatoires

Purified from culture supernatant of hybridoma cells grown in a bioreactor.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable