The Journal of biological chemistry, 269(51), 32299-32305 (1994-12-23)
The physiological alpha-oxoaldehyde methylglyoxal binds and modifies arginine, lysine, and cysteine residues in proteins. The kinetics and mechanism of these reactions were investigated with N alpha-acetylamino acids and bovine serum albumin at pH 7.4 and 37 degrees C. The reaction
Binding of methylglyoxal to albumin and formation of fluorescent adducts. Inhibition by arginine, N-alpha-acetylarginine and aminoguanidine.
T Selwood et al.
Biochemical Society transactions, 21(2), 170S-170S (1993-05-01)
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 21(2), 75-82 (2003-03-05)
Tissue accumulation of arginine (Arg), N-acetylarginine (NA), argininic acid (AA) and homoarginine (HA) occurs in hyperargininemia, an inborn error of the urea cycle. In the present study, we investigated the in vitro effects of Arg, NA, AA and HA on
Clinica chimica acta; international journal of clinical chemistry, 157(2), 143-150 (1986-06-15)
The concentrations of guanidino compounds in blood are raised in uraemic patients and may have toxic effects. The concentrations of 13 guanidino compounds in serum were measured in 29 patients with chronic renal failure treated by chronic intermittent haemodialysis using
Molecular genetics and metabolism, 100 Suppl 1, S31-S36 (2010-02-24)
The paucity of hyperammonemic crises together with spasticity, only seen in human arginase I deficient patients and not in patients with other urea cycle disorders, forces a search for candidates other than ammonia to associate with the pathophysiology and symptomatology.
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