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90374

Sigma-Aldrich

Sodium mercaptopyruvate dihydrate

97.0-103.0% (NT)

Synonyme(s) :

3-MP, 3-Mercapto-2-oxopropionic acid sodium salt dihydrate, 3-Mercaptopyruvic acid sodium salt dihydrate

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About This Item

Formule empirique (notation de Hill):
C3H3NaO3S·2H2O
Numéro CAS:
Poids moléculaire :
178.14
Numéro MDL:
Code UNSPSC :
12352201
ID de substance PubChem :
Nomenclature NACRES :
NA.25

Pureté

97.0-103.0% (NT)

Forme

solid

Composition

sulfur content, 17.5-18.5%

Couleur

white to off-white

Température de stockage

2-8°C

Chaîne SMILES 

O.O.[Na+].[O-]C(=O)C(=O)CS

InChI

1S/C3H4O3S.Na.2H2O/c4-2(1-7)3(5)6;;;/h7H,1H2,(H,5,6);;2*1H2/q;+1;;/p-1

Clé InChI

UTBPRNHFBUIAMM-UHFFFAOYSA-M

Actions biochimiques/physiologiques

Metabolite in cysteine and methionine metabolism, important intermediate in the mercaptopyruvate pathway, in which cysteine or aspartate transaminase catalyzes the transamination from cysteine to 3-mercaptopyruvate and then 3-mercaptopyruvate sulfurtransferase catalyzes the transsulfuration from 3-mercaptopyruvate to pyruvate, a process contributing to maintain the cellular redox status. It is a substrate for L-lactate dehydrogenase A chain, 3-mercaptopyruvate sulfurtransferase, Aspartate aminotransferase (mitochondrial), L-lactate dehydrogenase C chain, L-lactate dehydrogenase A-like 6A, Aspartate aminotransferase (cytoplasmic), L-lactate dehydrogenase B chain and L-lactate dehydrogenase A-like 6B.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Autres remarques

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Roderick A M Williams et al.
The Biochemical journal, 420(3), 451-462 (2009-03-20)
Genome mining and biochemical analyses have shown that Leishmania major possesses two pathways for cysteine synthesis--the de novo biosynthesis pathway comprising SAT (serine acetyltransferase) and CS (cysteine synthase) and the RTS (reverse trans-sulfuration) pathway comprising CBS (cystathionine beta-synthase) and CGL
Anthony Roucou et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 19(13), 1572-1578 (2018-03-31)
Room temperature millimeter-wave rotational spectroscopy supported by high level of theory calculations have been employed to fully characterise the conformational landscape of 3-Methoxyphenol, a semi-volatile polar oxygenated aromatic compound precursor of secondary organic aerosols in the atmosphere arising from biomass
Michael W Stutelberg et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1008, 181-188 (2015-12-15)
The current suite of Food and Drug Administration (FDA) approved antidotes (i.e., sodium nitrite, sodium thiosulfate, and hydroxocobalamin) are effective for treating cyanide poisoning, but individually, each antidote has major limitations (e.g., large effective dosage or delayed onset of action).
Ximing Li et al.
Bioresource technology, 315, 123833-123833 (2020-07-20)
In this study, the cross-talk between gama-aminobutyric acid (GABA) and calcium ion (Ca2+) signalling in the regulation of lipid production and cell growth in microalgae under fulvic acid and salinity stress (FA-salinity treatment) was investigated. GABA enhanced the lipid content
Heng Zhao et al.
PloS one, 8(6), e67322-e67322 (2013-06-28)
3-Mercaptopyruvate sulfurtransferase (3MST) is an important enzyme for the synthesis of hydrogen sulfide (H2S) in the brain. We present here data that indicate an exclusively localization of 3MST in astrocytes. Regional distribution of 3MST activities is even and unremarkable. Following

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