73156

N-Methyl-L-serine

≥98% (TLC)

• Synonyme(s) : (S)-3-Hydroxy-2-(methylamino)propionic acid, N-Me-Ser-OH
• Formule empirique (notation de Hill): C₄H₉NO₃
• Numéro CAS: 2480-26-4
• Poids moléculaire : 119.12
• Numéro Beilstein : 2498641
• Numéro MDL: MFCD00037756
• Code UNSPSC : 12352202
• ID de substance PubChem : 329764666
• Nomenclature NACRES : NA.32

Propriétés

• Pureté: ≥98% (TLC)
• Forme: powder
• Activité optique: [α]/D +9.5±1.0°, c = 1 in 1 M HCl
• Composition: carbon, 39.5-41.1% ; nitrogen, 11.5-12.0%
• Couleur: white
• Pf: 204 °C
• Chaîne SMILES: CN[C@@H](CO)C(O)=O
• InChI: 1S/C4H9NO3/c1-5-3(2-6)4(7)8/h3,5-6H,2H2,1H3,(H,7,8)/t3-/m0/s1
• Clé InChI: PSFABYLDRXJYID-VKHMYHEASA-N

Description

Actions biochimiques/physiologiques

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue. N-Methyl-L-serine stimulates hyaluronan production in human skin fibroblasts.

N-Methyl-L-serine has been found to stimulate production of high molecular mass hyaluronan in human fibroblasts. This effect was specific to methylated L-serine and not observed with other methylated amino acids.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable