The closest to MNF6 (detects CK 5, 6, 8, 17, and possibly 19) is CK cocktail AE1/AE3, which detects all but CK17. Oscar detects CK 7, 8, 18, and 19.
313M-1
Cytokeratin Cocktail (AE1 & AE3) Mouse Monoclonal Antibody
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About This Item
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41
Clone:
AE1 & AE3, monoclonal
application:
IHC (p)
Espèces réactives:
human
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
citations:
4
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Produits recommandés
Source biologique
mouse
Niveau de qualité
100
500
Conjugué
unconjugated
Forme d'anticorps
culture supernatant
Type de produit anticorps
primary antibodies
Clone
AE1 & AE3, monoclonal
Description
For In Vitro Diagnostic Use in Select Regions (See Chart)
Forme
buffered aqueous solution
Espèces réactives
human
Conditionnement
vial of 0.1 mL concentrate (313M-14)
vial of 0.5 mL concentrate (313M-15)
bottle of 1.0 mL predilute (313M-17)
vial of 1.0 mL concentrate (313M-16)
bottle of 7.0 mL predilute (313M-18)
Fabricant/nom de marque
Cell Marque™
Technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
Isotype
IgG1κ
Contrôle
breast, colon, prostate, skin
Conditions d'expédition
wet ice
Température de stockage
2-8°C
Visualisation
cytoplasmic
Informations sur le gène
human ... KRT1(3848)
Description générale
Anti-cytokeratin cocktail (AE1 & AE3) is a broad-spectrum keratin antibody cocktail. It is composed of mouse monoclonal antibody AE1 that recognizes acidic type I keratins and AE3 that reacts with basic type II keratins. Both clones were generated using epidermal keratin as immunogen. This antibody is useful for identifying cells of epithelial origin and detects most carcinomas of different primarysites. This antibody cocktail can cross-react with other intermediate filaments, such as glialfibrillary acidic protein, giving false-positive staining in glial tumors.
Qualité
 IVD |  IVD |  IVD |  RUO |
Liaison
Cytokeratin Cocktail Positive Control Slides, Product No. 313S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Forme physique
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Notes préparatoires
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Autres remarques
For Technical Service please contact: 800-665-7284 or email: [email protected]
Informations légales
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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Les clients ont également consulté
Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations.
D Cooper et al.
Laboratory investigation; a journal of technical methods and pathology, 52(3), 243-256 (1985-03-01)
V K Kriho et al.
Virchows Archiv : an international journal of pathology, 431(2), 139-147 (1997-08-01)
Several studies have shown that immunoenzymatic staining of formalin-fixed, paraffin-embedded astrocytomas with keratin antibodies frequently yields positive labelling, but no biochemical evidence of keratin expression in astrocytomas has been reported. We have investigated the presence of keratin in astrocytoma and
H Battifora
The American journal of surgical pathology, 12 Suppl 1, 24-42 (1988-01-01)
The past few years have seen great progress in our knowledge of the biology and the chemistry of intermediate filaments and other filamentous proteins. This has translated into the development of antibodies that, together with new, highly sensitive immunohistochemical methods
A M Gown et al.
American journal of clinical pathology, 84(4), 413-424 (1985-10-01)
A panel of monoclonal antibodies to human intermediate filament proteins was tested on an unselected series of 246 neoplasms. The antibody panel includes two different anti-cytokeratin antibodies, an anti-vimentin antibody, and an anti-neurofilament antibody (Gown and Vogel, Am J Pathol
Contenu apparenté
Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.
Aperçu de l'immunohistochimie diagnostique mettant en évidence son importance dans le diagnostic du cancer et la détection des maladies infectieuses en biologie médicale moderne.
Trusted IVDR-ready supplier of high-quality Cell Marque™ antibodies for diagnostic pathology and IHC, ensuring reliability and expert support.
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Is there a broad spectrum CK cocktail that is an equivalent to the Dako MNF116?
1 answer-
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