Y0000109

Thiomersal

European Pharmacopoeia (EP) Reference Standard

• Synonyme(s) : Acide 2-(éthylmercuromercapto)benzoïque sodium salt, Acide éthylmercurithiosalicylique sodium salt, Mercuro-([o-carboxyphényl]thio)éthyle sodium salt, Éthylmercurithiosalicylate de sodium
• Formule linéaire : 2-(C₂H₅HgS)C₆H₄CO₂Na
• Numéro CAS: 54-64-8
• Poids moléculaire : 404.81
• Beilstein: 8169555
• Numéro MDL: MFCD00013062
• Code UNSPSC : 41116107
• ID de substance PubChem : 329830849
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: thimerosal
• Fabricant/nom de marque: EDQM
• Pf: 234-237 °C (dec.) (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: [Na+].CC[Hg]Sc1ccccc1C([O-])=O
• InChI: 1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
• Clé InChI: RTKIYNMVFMVABJ-UHFFFAOYSA-L

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Thimerosal EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Le thimérosal est un réactif oxydant les groupements sulfhydryle (thiol) qui est capable d'inhiber de multiples protéines et enzymes dépendantes de groupements sulfhydryle telles que la méthionine synthase dépendante de la PI3-kinase, les récepteurs transporteurs du glutamate et les ATPases dépendantes de Na⁺+K⁺.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Clause de non-responsabilité

As part of the corporation global plan to support the Minamata Convention in eliminating mercury-containing compounds, as of January 2021 customers will be required to provide an End-Use Declaration. The sales of thimerosal will be restricted for approved applications only, such as preservative in vaccine manufacturing, preservative in eye cosmetics, research use within academia (excluding preservation intent) and as reference material only.

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act , European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H310 + H330,H373,H410
• Conseils de prudence: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Classification des risques: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
• Organes cibles: Kidney
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable